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tadalista should be taken with a full glass of water. They should be taken 30 minutes bore sexual intercourse. You should not take the pills if you have high blood pressure or are under medication for an irregular heartbeat. You should not take it if you have diabetes or are allergic to Tadalafil. You should not take medicine if you have a history of eye problems. You should not take it if you are pregnant or planning to become pregnant. You should not take it if you suffer from kidney or liver problems.