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active 2 years agoPeople with Fildena Professional pill erectile dysfunction have low levels of cGMP, a neurotransmitter that triggers erections by transmitting sexual processes from the brain to the penis. However, in the picture, an enzyme called phosphodiesterase type 5 (PDE5) interferes with the focus of cGMP in the picture. When PDE5 goes up and cGMP goes down, the muscles and blood vessels of the penis lose flexibility. They contract to maintain the shape on the penis, preventing the penis from obtaining a stable erection.